Abstract
Objective: We aimed to investigate the effect of phototherapy on plasma alpha-melanocyte-stimulating hormone (α-MSH) levels of newborns with indirect hyperbilirubinemia (IHB) for the first time. Materials and Methods: A total of 45 cases, who were hospitalized in neonatal intensive care units between July 1, 2019, to September 30, 2019, and received phototherapy, were retrospectively included in the study. Plasma α-MSH and bilirubin levels were measured before and after the phototherapy. Results: A total of 45 newborns (19 girls and 26 boys) were included in to study. The average birth weight was 3202 grams and the mean total bilirubin level was 17.2 mg/dL. α-MSH levels before and after phototherapy were 326.2 (4.0-2228.0) ng/L and 373.9 (8.7-2283.0) ng/L, respectively and did not represent a significant difference (p>0.05). Conclusion: This study demonstrated that there was no effect between phototherapy applied for newborn IHB and plasma α-MSH levels.
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