Abstract

The constructivist model of learning is that concepts are built in the mind of the learner. Biochemistry is a cumulative field, and builds on concepts from general chemistry, organic chemistry, and general biology. The hypothesis of this study is that by correcting errors in these underlying concepts and connecting biochemistry learning to prior concepts will cause better understanding of both the prerequisite knowledge and biochemistry. Students completed activities either targeted at key prerequisite concepts or control activities on a weekly basis. Targeted concepts included equilibrium, bond energy, acid/base chemistry, hydrogen bonding, free energy, stereoisomers, protein function, and alpha helices. Performance was evaluated on a pre/post test of the targeted concepts and on specific questions of a biochemistry final exam.Grant Funding Source: Supported by NSF‐TUES grant #1140711

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