Abstract
In order to achieve the multi-claim products required for the dental care category, it is necessary for the formulator to use a variety of different ingredients. This places a number of demands on the development process. Innovations in the areas of pharmaceutical technology have contributed to the formulation of the products having superior efficacy as well as other attributes that may contribute to clinical response and patient acceptability. Improved clinical efficacy and tolerability, along with conditioning signals, should encourage patient compliance with oral hygiene further complementing professional efforts directed at disease prevention. The most effective way of preventing the development of dental disease is in controlling the production of dental plaque. It is formed by microbial action. The removal of plaque from the teeth and related areas is essential for the maintenance of a healthy mouth. In this paper we have presented the main components of toothpastes and mouthwashes. For the active ingredients, their supposed effect as therapeutic agents is also explained.
Highlights
Ingredients of toothpastes and mouthwashesA toothpaste in defined as a semi-solid material for removing naturally occurring deposits from teeth and is supposed to be used simultaneous with a toothbrush
In order to achieve the multi-claim products required for the dental care category, it is necessary for the formulator to use a variety of different ingredients
This places a number of demands on the development process
Summary
A toothpaste in defined as a semi-solid material for removing naturally occurring deposits from teeth and is supposed to be used simultaneous with a toothbrush. The following substances are widely used abrasives, which satisfy these conditions: Calcium carbonate (CaCO3) A fine, white, odourless, microcrystalline powder, practically insoluble in water (3). Sodium alginate has little surface activity and its emulsifying power is achieved by increasing the viscosity of the aqueous phase It is used as a suspending and thickening agent and in the preparation of water-miscible pastes, creams and gels. Edina Vranic et al.: FORMULATION INGREDIENTS FOR TOOTHPASTES AND MOUTHWASHES www.bjbms.org Carbomers These are synthetic high molecular weight polymers of acrylic acid cross-linked with polyalkenyl ethers of sugars or polyalcohols. Hygroscopic powders with a slight characteristic odour They swell in water and in other polar solvents after dispersion and neutralisation with sodium hydroxide solution (6). Alcohol is used in mouth rinses (mouthwashes) as a solvent and taste enhancer
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