Formulation, Development and Characterization of Oral Jelly to Improve Therapeutic Effectiveness

Abstract

The oral route is the most convenient and has great effectiveness in taking new chemical entities; hence it has improved patient acceptance. However, the main limitations associated with such formulations involve unpleasant or bitter taste as well as problems related to swallowing and reduced bioavailability of chemical entities. When it comes to children, the main limitation is they cannot safely swallow the medications in the form of tablets and capsules. But kids, even those without teeth, can swallow the jelly easily. As in the development of new dosage forms for every child, taste, color, smell, texture, and appearance are important factors in improving patient compliance. Children refuse to tolerate the same medication again, which becomes a big problem for parents trying to take the medication. An effective way to solve such types of problems involves the production of children’s friendly dosage formulations with attractive and eye catching taste, smell, color as well as texture. The most identical characteristic of oral jelly as dosage form is that it are easy to chew and dissolves rapidly in saliva so no water is required. Moreover, the good texture and appearance make it easy to attract patients as well as to improve patient compliance. Above all, it provides a soft and beautiful texture, causing no discomfort to patients.