Formulation and Quality Control of Readily Dissolving Drink Powder from Antidesma ghaesembilla Fruits

Abstract

Antidesma ghaesembilla Gaertn, known as in Thai, is a plant with edible purple compound fruits. This experiment was conducted to investigate the 1,1-diphenyl-2-picrylhydrazyl (DPPH)-scavenging activities of extracts from the fruits of mamao prepared by different methods of extraction and drying, and to quantitatively analyze the total phenolic content and the total anthocy- anin content. Decoction and drying by evaporating the extract of mamao ripe fruits promoted the extract with the strongest free radical scavenging activity (IC 50 = 72.42 ± 3.52 µg/ml), with high amounts of total phenolic content and total anthocyanin content of 1.22 ± 0.36 g gallic acid equivalent in 100 g extract (g%GAE) and 7.09 ± 0.24 g cyanidin-3-glucoside equivalent in 100 g extract (g%C-3-GE), respectively. This extract was developed as a readily dissolving drink powder by a wet granulation method and qualitatively controlled by evaluations of loss on drying, thin layer chromatographic (TLC) and infrared spectroscopic (IR) fingerprints. The obtained product was observed to be a pinkish-red pow - der that contained 3.08 ± 0.81 g%C-3-GE in 1 sachet (14 g) and exhibited free radical scavenging activity equivalent to 0.004 g of vitamin C.