Abstract
Hair growth tonics containing herbal and synthetic ingredients have been developed to overcome hair loss and baldness. Advanced technological developments made many Indonesians prefer to use herbal products compared to synthetic products due to their fewer side effects. Green tea leaves (Camellia sinensis L.) is a plant believed to increase hair growth rates due to its flavonoid compounds. The purpose of this study is to formulate hair tonic from water fraction ethanolic extract green tea leaves, to look at the activity of hair growth-promoting, and also to look at physical stability, irritation tests, and microbial contamination. The positive control used is 2% Minoxidil. The hair growth activity test was carried out by applying a hair tonic to rabbits. Hair growth measurement data were statistically tested by the ANOVA test. The formulated green tea leaves tonic met the physical properties test. The tonic produces similar growth activities with the positive control (significance difference (p> 0.05)). In addition, the tonic does not have a skin irritation effect on rabbit skin and is free from bacteria.
Highlights
The benefits of green tea leaves as a hair growth-promoting have been proven by Lamria (2013) that 2.5% green tea leaves extract in hair tonic preparations increased hair growth rates significantly compared to Minoxidil 2.5%
This study aims to formulate hair tonic from water fraction ethanolic extract green tea leaves, look activity of hair growth-promoting, and to look physical stability, irritation tests, and microbial contamination
Ethanolic extract from green tea leaves and water fraction was made refers to the method of Noviani et al (2019)
Summary
Hair has an important role in humans. Hair regulates temperature, facilitates sweat evaporation, and stimulates a sensitive sense of touch. The benefits of green tea leaves as a hair growth-promoting have been proven by Lamria (2013) that 2.5% green tea leaves extract in hair tonic preparations increased hair growth rates significantly compared to Minoxidil 2.5%. Noviani et al (2019) proved that the ethyl acetate and water fractions of ethanolic extract of green tea leaves contained flavonoids, so it could continue the hair growthpromoting activities with concentrations of 1% and 4%, but the result showed that 4% of water fraction containing flavonoids had the best hair growth-promoting activity. Based on the data above, in this study, 4 % of the water fraction of ethanolic extract green tea leaves will be formulated to be hair tonic. This study aims to formulate hair tonic from water fraction ethanolic extract green tea leaves, look activity of hair growth-promoting, and to look physical stability, irritation tests, and microbial contamination. Minoxidil was used as a positive control in this study because the reason for this study was to find natural compounds that can replace synthetic compounds that have side effects
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