Formulation and evaluation of serratiopeptidase and salbutamol tablet for dysphagia

Abstract

Oral Dispersible Tablet of Serratiopeptidase and salbutamol were prepared, evaluated and different types of concentration and dissolution of tablets were studied. In FTIR, drug and excipients with their mixture showed that there is no interaction between the drug molecule and excipients used. The Percentage of drug content of tablets in the formulations was found to be 95 % to 105% which complies with the limits of pharmacopoeia. By the process of direct compression method was used to prepare oral Dispersible tablet containing 300 mg of Serratiopeptidase and salbutamol. formulation was conducted using different concentrations of croscarmellose, micro crystalline cellulose, as a super disintegrants. And their interaction with Serratiopeptidase and salbutamol also evaluated using FTIR.