FORMULATION AND EVALUATION OF PHARMACEUTICALY STABLE SERUM OF DUCHESNEA INDICA (ARBENAN)

Abstract

Objective: Arbenan (Duchesnea indica) plants contain saponins, flavonoids, and tannins which have antioxidant activity. The purpose of this research is to perform formulation and evaluation extract ethanol of Arbenan leaves in the form of serum which is pharmaceutically stable.
 Method: Arbenan leaf powder was macerated with ethanol solvent, and then left for 3-4 days while stirring repeatedly, and then filtering. Furthermore, the liquid ethanol extract that has been obtained is evaporated using a Rotary Vacum Evaporator was used to evaporate the extract. Prepared extract was used to evaluate various parameters like organoleptics, homogeneity, viscosity, and pH.
 Result: All formulations were having typical smell, light brown color and a little thick consistency. Formulations of leaf extract of Arabenan with four variations bases have shown to have good stability after stress condition. It can be seen from the evaluation result are organoleptics, homogeneity, viscosity, rheology, and pH.
 Conclusion: Study concludes that a stable leaf extract of Arabenan can be effectively formulated into a serum by the means of various bases.
 
 Peer Review History: 
 Received 8 January 2021; Revised 13 February; Accepted 4 March, Available online 15 March 2021
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 Received file: Reviewer's Comments:
 Average Peer review marks at initial stage: 5.0/10
 Average Peer review marks at publication stage: 7.0/10
 Reviewer(s) detail:
 Dr. Marwa A. A. Fayed, 
 University of Sadat City, Egypt, maafayed@gmail.com
 Prof. Dr. Ali Gamal Ahmed Al-kaf, 
 Sana'a university, Yemen, alialkaf21@gmail.com
 Ahmad Najib,
 Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id
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