Abstract
Abstract: Ketoconazole is a broad spectrum imidazole antifungal agent marketed as creams and tablets. It interacts with 14- demethylase, a cytochrome P-450 enzyme and inhibits ergo sterol synthesis and increased fungal cellular permeability and is used against a wide variety of fungi and yeast .Nano technology scales up to one billionth of a meter Generally, they are considered to be in range of 100nm to 1000nm. Ketoconazole Nano emulsion drug delivery system is known to improve dissolution characteristics of a poorly water soluble drug since they maintain the drug in a dissolution characteristics of a poorly water soluble drug since they maintain the drug in solubilized state. Using the optimized Nano emulsion of ketoconazole loaded were prepared. The prepared liquid Nano emulsion are subjected to thermodynamic stability testing and zeta potential due to their characteristics size and properties which included kinetic stability; they are effective L solubilizing the drug and transferring them to words the target areas. It is characterized for droplet size, ze potential, viscosity, in vitro drug release study we performed.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
