FORMULATION AND EVALUATION OF KALYANAKA KSHARA: AN AYURVEDIC COMPOUND FORMULATION

Abstract

Background: Ayurveda utilises different forms of herbs in therapeutics. Kshara is one such form. The material destroys or cleans the excessive/morbid doshas (Ksharanat Kshananat va Kshara). They are considered anushastra’s (para-surgical instruments). Kshara’s (alkaline substances) are more suitable and can be used where shastra chikitsa (surgery) is contraindicated. Kshara (alkaline substances) is the best drug for internal and external use. Considering the quick action, lesser dose, and more comprehensive action, an attempt is made to formulate and standardise the product, as there is insufficient data regarding its standardisation. Objective: To formulate and standardise the Kalyanaka Kshara. Methods: All ingredients were taken per the reference Ashtanga Hridaya chikitsa sthana, Kalyanaka Kshara. All the Raw materials like plants, animals, and mineral drugs were collected from the local market of Jhansi, Uttar Pradesh. And by the sharava samputa (earthen pot) method, three different samples (KK1, KK2, and KK3) of Kalyanaka Kshara were prepared. Result: Physicochemical changes in each sample, organoleptic characters of the product yield were observed. The standard values of Kalyanaka Kshara are alkaline with pH 10.01, loss on drying (% w/w) 0.47, total ash value (% w/w) 55.5, acid insoluble ash value (% w/w) 0.93 water extractive value (% w/w) 62.55, alcohol extractive value (% w/w) 38.54. Conclusion: On behalf of each sample's pharmaceutical and physicochemical analysis, there are no considerable changes in any of the KK1, KK2, and KK3 samples, and encouraging results were observed. The developed SOP and physicochemical parameters can be adopted as pharmacopeial standards.