Abstract

Abstract: Neem, “the bitter gem” is one of the most valued trees with many medicinal applications. The scientific name of neem is Azadirachta indica and belongs to Meliaceae family. It is the world’s most studied tree in the world and most promising one in the 21st century. Every part of the tree has medicinal value, such as flowers, leaves, neem cake, fruits and seed oil. Almost 300 different phytochemicals have been found in neem tree with versatile application. The aqueous and alcoholic leaf extract of neem is accounted for to have different pharmacological activities . In current situations oral dental care with use of herbal toothpaste containing natural ingredients are more acceptable in public belief than chemical based synthetic formulations due to their safety and efficacy in reducing dental caries, and preventing other dental issues to which this generation is prone to. In this formulation we utilizes clove oil, neem extract, peppermint oil, which are used in this research work. These extracts possess many activities like anti-ulcer, anti-caries, anti- bacterial, wound healing along with which it certain special additional properties like anti-fungal and anti – microbial . Important physical parameters i.e. pH, stability, spreadability, foamability, to make a successful more efficacious and stable formulation. This study that our herbal based toothpaste formulation having natural ingredients.

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