Abstract
The aim of present study was to formulate and evaluate herbal gel containing Solanum nigrum extract for prevention of wound healing. Topical gel formulation was designed by using Solanum nigrum extract as API and HPMC E5 as a gelling agent. The herbaceous plant Solanum nigrum (kamuni) reported for healing action and newer research studies and methodologies are being carried to find active chemical constituents which not only promise fast healing but also will reduce the complication and cost. Extracts of this medicinal plant are useful in the treatment of several health problems such as bacterial infections, ulcer, cancer, tuberculosis, arthritis and inflammatory. The plant Solanum nigrum (kamuni) leaves is the best traditional medicine for the study of wound healing activity. The concept of wound healing is changing from day to day. Ayurveda is the richest source of plant drugs for management of wounds and Solanum nigrum L. is one such. The plant is used as haemostatic and wound healing agent from ethno pharmacological point of view. The prepared gel was characterized for their physicochemical parameters i.e., preliminary phytochemical analysis, quantitative analysis, appearance, spreadability, pH, viscosity, in-vitro diffusion study and stability study.
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