Formulation and Evaluation of Antimicrobial Ointment from Acacia auriculiformis Leaves Extract

Abstract

The current experiment aims to create and test an ointment with an ethanolic extract from Acacia auriculiformis for antimicrobial action. The soxhalation procedure was used to create the ethanolic extract. After producing the ointment base, five batches of ointments were created by incorporating the extract into the base. Physical and chemical properties of each formulation, including color, flavor, pH, spreadability, consistency, solubility, and washability, were assessed. The formulation’s stability at different temperature conditions was also assessed, and the results show that neither its irritancy nor its spreadability has changed. F5 was discovered to be the ideal formulation among the ointment batches. It has a larger zone of inhibition over both gram-positive and gram-negative bacteria.