Abstract
Matoa (Pometia Pinnata) is a typical Papua fruit plant, classified as a large tree with an average height of
 18 meters with a maximum average diameter of 100 cm. Generally bear fruit once a year, flowering in
 July to October and fruiting 3 or 4 months later. Some research shows that the leaves, fruit bark and matoa
 tree bark contain tannins, saponins and alkaloids. The purpose of this study was to produce a formulation
 and test the effectiveness of a cream extract of matoa tree bark (pometia pinnata) honey combination on
 staphylacoccus aureus bacteria. This research is a purely experimental research to produce an extract of
 the matoa tree bark cream and then test its effectiveness in the treatment of staphylococcus aureus bacteria,
 with a completely randomized design (CRD) design. The results showed that the matoa rind extract cream
 was effective against staphylacoccus aureus bacteria with a significant value of 0.00 <0.005. This study
 recommends a combination of honey bark stem extract cream for the treatment of staphylococcus aureus
 bacterial infections.
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