Formulation and comparison of alternative multiscale models for drum granulation

Abstract

Continuous granulation of powders is a unit operation that poses both operational and modelling challenges. We discuss the formulation of several alternative multiscale models for a drum granulator. All combine a vessel scale population balance model with a granule scale discrete element method (DEM) model, but they are linked using different multiscale integration frameworks. The inter-scale flow of information and the potential applications of the alternative models are outlined.