Abstract
A decrease in the hormone estrogen in women can trigger changes in nutritional status and cholesterol levels that cause hypercholesterolemia, so that antioxidant compounds and fiber are needed to improve one of them is in tempeh flour and rice bran. This study aims to prove the effect ofgiving a combination of tempeh flour and bran (Petul) on nutritional status and total cholesterol levels in menopausal women with hypercholesterolemia. Methods: Randomized control group pretest posttestcontrol group design, carried out on 60 menopausal women at least 1 year with hypercholesterolemia, not taking medication who were divided into intervention groups (given a formula 37.33 g / drink 3 times a day for 3 weeks) and placebo in the control group. The variables studied before and after the intervention were nutritional status and total cholesterol levels.Independent statistical analysis of t test, dependent t test and Ring spearmen correlation test. Results: Combination of PETUL as much as 37.33 g / drink 3 times / day for 3 weeks can improve nutritional status but has no significant and significant effect on reducing total cholesterol levels. Consclusion : PETUL formula can improve nutritional status and reduce total cholesterol levels.Keywords: Formula, Petul, nutritional status, menopausal women, hypercholesterolemia
Highlights
150 mg/dl menjadi 260 mg/dl, maka akan meningkatkan resiko penyakit jantung menjadi tiga kali lipat.(World Health Organization, 2008)
Kedelai mengandung antioksidan berupa isoflavon merupakan suatu fitoestrogen yang dapat berikatan dengan reseptor endogen dan bersifat kardioprotektif karena bertindak menyerupai estrogen sebagai antioksidan yang menetralisir radikal bebas dengan cara memberikan efek terhadap peningkatan aktivitas up regulating reseptor kolestarol LDL kemudian akan meningkatkan kolesterol LDL clearances dari peredaran darah dan mengurangi kadar kolesterol LDL dalam darah (Ilsakova,et al, 2010; Cena ER, et al 2011)
Am J Clin Nutr 2005; 81: 397-408 http://jurnal.unimus.ac.id
Summary
Temanggung, mengalami dislipidemia, tidak mempunyai riwayat atau sedang mengalami penyakit hati, ginjal, gangguan tiroid, kanker, PJK, stroke, diabetes mellitus, tidak mengkonsumsi suplemen, tidak mengkonsumsi obat hipoglikemi, fitofarmaka, hipolipidemia., penganut vegetarian dan menggunakan terapi estrogen serta bersedia untuk mengukuti proses anamnesis, pemeriksaan fisik, antropometri, dan penapisan pemeriksaan darah. 60 wanita menopause dengan dislipidemia yang diambil dengan cara consecutive sampling. Sebanyak 60 sampel kemudian dilakukan randomisasi untuk menentukan subjek masuk dalam kelompok kontrol dan kelompok intervensi.Penentuan status gizi dilakukan dengan menimbang BB menggunakan timbangan dacin digital sedangkan pengukuran tinggi badan menggunakan microtoice.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
