Formation renal function in children born prematurely

Abstract

A premature baby needing resuscitation after birth, is exposed to damaging factors affecting the entire body, including the kidneys. Aim — analysis of current data on the issue of the formation of kidney function in children born prematurely. Materials and methods. The review publications domestic and foreign authors studied data from randomized clinical and epidemiological studies. Results and discussion. Events intensive care, which include mechanical ventilation, infusion therapy, parenteral nutrition, intravenous drugs, lead to an increased load on the immature kidney premature baby in the neonatal period. A special risk factor for preterm is still imperfect glomerular and tubular function, renal large capillary surface, high renal blood flow, inadequate regulation of acid-base balance and the ability to concentrate, are under the influence of external loads become insolvent. Under the influence of damaging factors on the kidney nephron deficit increases the risk of further decline in kidney function. It is assumed that no additional nephrons deficit is not negative factors leads to chronic diseases in the future. Conclusion. Analyzing conducted research on the formation of kidney function in children born prematurely, it can be assumed that children with a gestational age less than 32 weeks and weighing less than 1500 grams at birth, who are exposed to adverse environmental factors on the developing buds in the perinatal and neonatal periods. They are in the zone of risk of chronic disease of the kidneys in later life.