Abstract

3H-labeled particles with the density of intact mengovirus in CsCl were detected following the incubation of cell-free extracts from mengovirus infected cells with 3H-UTP in a RNA polymerase reaction mixture. The 3H-particles contained complete strands of 3H-labeled 35 S mengovirus RNA. The viral-like particles were found in the region of a sucrose gradient (150–250 S) where viral-specific RNA polymerase activity is detected.

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