Abstract
A novel conductive DNA-based nanomaterial, DNA-peptide wire, composed of a DNA core and a peripheral peptide layer, is presented. The electrical conductivity of the wire is found to be at least three orders in magnitude higher than that of native double-stranded DNA (dsDNA). High conductivity of the wires along with a better resistance to mechanical deformations caused by interactions between the substrate and electrode surface make them appealing for a wide variety of nanoelectronic and biosensor applications.
Highlights
During the last two decades, DNA has become one of the cornerstones of nanotechnology
Under the same experimental conditions, double-stranded DNA (dsDNA) stretched on the substrate exhibited a very poor electrostatic contrast, even when the tip bias voltage in electrostatic force microscopy (EFM) experiments was increased to ±8 V and the lift distance was lowered down to 10 nm (Figure 2a)
In agreement with the EFM measurements, the I-V curves obtained for dsDNA molecules combed across two adjacent nanoelectrodes (Figure 2b) indicated currents within the noise level (~50 fA)
Summary
During the last two decades, DNA has become one of the cornerstones of nanotechnology. The understanding of both experimental and theoretical aspects of DNA conductivity is far from complete, the growing body of evidence suggests that short dsDNA molecules (
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