Abstract
Allyl boronic acids are more reactive allylating reagents than their boronate ester counterparts. However, isolation of these species is difficult as they rapidly decompose under solvent-free conditions. The authors have developed a way of generating allyl boronic acids in situ and of reacting them directly with aldehydes and ketones. Thus, this method gave a highly stereoselective access to homoallylic alcohols and unnatural α-amino acids.
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