Abstract
Lamellar structure of phospholipid vesicles, obtained by short time ultrasonic radiation, was studied by using negative stain electron microscopy. It is expected that the number of lamellae are randomly distributed over a possible region which is determined by size of the fragments torn by the radiation. However, a more restricted distribution in the number of lamellae was observed, e. g., there were no larger unilamellar vesicles and no vesicles with a larger number of lamellae. The result could be explained in terms of the interbilayer interaction and the bending elastic energy considering the high curvature effect of bilayers. This suggested that sonicated vesicles were formed inorder to take a mechanically stable lamellar structure.
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