Abstract
AbstractBackgroundSalamanders stand out among vertebrate animals in two key characteristics: their ability to regenerate body parts, and their large and variable genome sizes.ResultsHere we show how to unite seemingly disparate facets of salamander biology, regeneration ability, and genome size variation, into one synthetic view. Large and variable genome sizes may be the key to understanding the prodigious ability of most salamanders to regenerate damaged or lost body parts. We report a correlate of genome size variation that has been previously neglected: the impacts of genome size on the structure and function of the genes themselves. Salamanders are, in essence, paradoxically much younger, especially at the cellular level than their chronological age would suggest.ConclusionsBecause of the large size and range of variation in genome size in salamanders, we hypothesize that this relationship uncouples a dynamic interaction between growth and differentiation in processes of morphogenesis, pattern formation, and regeneration in ways that are unique among vertebrates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.