Abstract

Variable number of repeat (VNTR) base sequences are one of the most informative genetic DNA-polymorphisms for identification purposes. We have implemented the analysis of VNTR-loci at the Netherlands Forensic Science Institute using the Single Locus Probe hybridization technique. This technique is essentially the same one as agreed upon by the European DNA Profiling (EDNAP) group [3[. The forensic use of this technique is regarded as valid and reliable [1,2]. However, interpretation of the test results is highly dependent on the population genetics of the various DNA-markers and the forensic validation of this DNA-test in the Netherlands requires: 1. the implementation of match criteria for the comparison of DNA-profiles. 2. the collection of allele frequency data from the relevant population(s).

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