Abstract
In this study we report the application of a minisequencing panel of 52 SNPs of the mtDNA, which allows the determination of the major world-wide mitochondrial haplogroups, in highly degraded samples. A total of 25 human remains from a mass grave of the Spanish Civil War (1936–1939) were analyzed in order to define their corresponding mtDNA haplogroup and, subsequently, investigate possible maternal relationships with the available reference samples. The results highlight the potential of this 52 mtSNP panel as an efficient screening method that can be used as an alternative or complementary approach to mtDNA sequencing in order to discriminate among maternal lineages in highly degraded DNA samples.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Forensic Science International: Genetics Supplement Series
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
