Abstract
Foreign body reaction (FBR) is a granulomatous inflammation characterized by the inclusion of foreign material not digested by macrophages. Woman, 42, had her sporadic pain in the mental region evaluated. It had been present for 12 years, but symptoms became more frequent in the last 2 months. She experienced facial trauma in 1987. Radiographs were normal, but computed tomography (CT) showed bone destruction from the right canine to the mandibular ramus with exposed dental roots. Incisional biopsy confirmed the FBR diagnosis. Histopathological examination showed bone partially replaced by dense connective tissue with mononuclear infiltrate and granulomas composed of multinucleated giant cells and epithelioid macrophages. Conservative treatment with curettage was performed under general anesthesia. FBR evolution can take a few months to several years. Generally it is asymptomatic for long periods; symptoms develop as the lesion increases and causes bone loss and local nerve exposure.
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