Foreground stimuli and task engagement enhance neuronal adaptation to background noise in the inferior colliculus of macaques.

Abstract

Auditory neuronal responses are modified by background noise. Inferior colliculus (IC) neuronal responses adapt to the most frequent sound level within an acoustic scene (adaptation to stimulus statistics), a mechanism that may preserve neuronal and behavioral thresholds for signal detection. However, it is still unclear whether the presence of foreground stimuli and/or task involvement can modify neuronal adaptation. To investigate how task engagement interacts with this mechanism, we compared the response of IC neurons to background noise, which caused adaptation to stimulus statistics, while macaque monkeys performed a masked tone detection task (task-driven condition) with responses recorded when the same background noise was presented alone (passive listening condition). In the task-dependent condition, monkeys performed a Go/No-Go task while 50-ms tones were embedded within an adaptation-inducing continuous background noise whose levels changed every 50 ms and were drawn from a probability distribution. The adaptation to noise stimulus statistics in IC neuronal responses was significantly enhanced in the task-driven condition compared with the passive listening condition, showing that foreground stimuli and/or task-engagement can modify IC neuronal responses. Additionally, the response of IC neurons to noise was significantly affected by the preceding sensory information (history effect) regardless of task involvement. These studies show that dynamic range adaptation in IC preserves behavioral and neurometric thresholds irrespective of noise type and a dependence of neuronal activity on task-related factors at subcortical levels of processing.NEW & NOTEWORTHY Auditory neuronal responses are influenced by maskers and distractors. However, it is still unclear whether the neuronal sensitivity to the masker stimulus is influenced by task-dependent factors. Our study represents one of the first attempts to investigate how task involvement influences the neural representation of background sounds in the subcortical, midbrain auditory neurons of behaving animals.