Follow-up value of 3 T magnetic resonance angiography after intracranial aneurysm coil embolization： a meta-analysis

Abstract

Objective To evaluate the follow-up diagnostic value of 3T magnetic resonance angiography （MRA） after intracranial aneurysm coil embolization. Methods The databases such as PubMed, EMhase, Cochrane Library, CBM, CNKI and VIP were retrieved. According to the inclusion criteria of diagnostic tests, the diagnostic tests of the follow-up diagnostic value about MRA were screened after intracranial aneurysm coil embolization. The methodological quality included in the studies was evaluated using QUADAS items and the meta-analysis was conducted using Meta-Disc 1.4 software. The receiver operating characteristic curve was drawn and the area under the curve was calculated. The residual sensitivity and specificity diagnosed by MRA after intracranial aneurysm embolization were evaluated. Results A total of 6 studies were included, including 253 patients. The pooled sensitivity and specificity in 3 T MRA diagnosing residual intraeranial aneurysms were 0. 915 （95% confidence interval [CI] 0. 850 -0. 959） and 0. 847 （95% CI 0. 787 -0. 896） respectively. The area under the receiver operating characteristic curve was 0. 951, Q =0. 892. Conclusions 3 T TOF MRA can be used as an effective and feasible imaging follow-up method after embolization of intracranial aneurysnas, however, because of the methodological limitations, the high-quality research is needed to further validate the application value of the MRA during follow-up after intracranial aneurysm embolization. Key words: Intracranial Aneurysm; Embolization, Therapeutic; Magnetic Resonance Angiography; Follow-Up Studies; Sensitivity and Specificity; Meta-Analysis