Abstract
Between 1968 and 1981, 138 patients (101 male and 37 female) with a mean age of 38 years were operated on for chronic pancreatitis at the Department of General Surgery, University of Göttingen. Pathogenetic factors were alcohol abuse in 65%, biliary diseases in 14% and unknown in 20%. Surgical therapy included 51 resections (37%) (4 total pancreatectomies, 24 Whipple’s procedures and 23 left pancreatectomy). Drainage operations were performed in 68 patients (49%) (24 pancreaticojejunostomies and 44 cystojejunostomies). Intervention of neighboring organs were performed 23 times. The mean follow-up period was 10 years (4–14 years), the late mortality rate in drainage operations (15 and 19%) was twice as high as after resection procedures (7.5%). Recurrences occurred in 16 % after resections but in 41 % after drainage operations. Latent or manifest diabetes was observed in 21 % after drainage operations but in 63% in the resection group. From these data we conclude that both alcohol withdrawal and the type of planned operations are important factors in the prognosis of chronic pancreatitis.
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