Abstract

The emergence of the primary and acquired drug resistance mutations (DRM) poses a significant threat to successful antiretroviral therapy (ART) against HIV-infection. The WHO/UNAIDS 90–90–90 targets [1] are that 90% of the people living with HIV (PLHIV) know their HIV-status, and, of them, 90% are accessing therapy; finally, of those who are accessing treatment, 90% should have suppressed viral loads. The success of this strategy highly depends on the prevention and monitoring of the pretreatment drug resistance (PDR) and acquired drug resistance (ADR).

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