Abstract
Follicular mucinosis (FM) is a rare disorder of the skin characterized by follicular degeneration due to the accumulation of mucin within the pilosebaceous unit, with associated inflammatory changes. We report a case of an 11-year-old female with widespread lesions showing distinct clinical and histological features of FM with a brief review of the literature.
Highlights
Follicular mucinosis is a rare cutaneous mucinosis characterized by accumulation of mucin at the external root sheath and sebaceous glands [1]
Follicular mucinosis was first described by Pinkus as alopecia caused by follicular degeneration secondary to the accumulation of mucin around the outer hair sheath and sebaceous gland, with prominent follicular infiltration by chronic inflammatory cells [3]
Subsequent evidence revealed that this unique degeneration of the pilosebaceaous unit can occur in the presence or absence of alopecia, the name Follicular mucinosis (FM) [45]
Summary
Follicular mucinosis is a rare cutaneous mucinosis characterized by accumulation of mucin at the external root sheath and sebaceous glands [1]. It manifests clinically as follicular papules distributed on the trunk, proximal limbs, scalp, and face; it may exist as indurated plaques [2]. An 11-year-old female was referred to our center with multiple skin papules of 11 months duration. She was on no medications at the time. Examination revealed widespread follicular papules which were located mainly on the elbows, knees, buttocks, and lower back (Figures 1-2). At 4 months followup, there was progressive improvement of symptoms with only mild residual papules of the elbows and buttocks
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