Abstract

ABRIEF review of the literature on blood changes in follicular lymphoma disclosed that in the cases reported by Brill, Baehr, and Rosenthal 1 the blood picture was normal. The majority of later cases also appeared to be associated with normal red blood cell count and hemoglobin values. Sometimes slight anemia was observed. 2 According to Gall and associates, 3 anemia (a count of 3,500,000 red blood cells or less) was found in 18% of their 63 follicular lymphoma cases, compared with an incidence of 39% in their cases of other lymphomas. They frequently noted anemia as a terminal manifestation, perhaps due to long-continued irradiation. Meyer 4 reported marked anemia in one of six cases; moderate anemia in two, and no anemia in three cases. Mayer and Thomas 5 found terminal normocytic anemia in all their cases. The anemia was severe in only two cases. One patient, with normal results on bone marrow study, reacted well

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