Abstract

AbstractFolic acid, present in different chemical forms of folates in the diet, is essential for cell division, biosynthesis of DNA and RNA, and growth. Furthermore, folates together with vitamin B12, are cofactors in the metabolism of homocysteine. During the past few years the requirement of dietary folate intake has been debated. The need is particularly high before, during and after the conception to prevent neural tube defects (NTD). There are also indications of a protective effect against cardiovascular disease and associations with the development of mental degenerative disorders such as Alzheimer’s disease. Knowledge of the folate content in different foods, as well as the bioavailability of folates from different foods, is essential. In this issue of the Scandinavian Journal of Nutrition, Cornelia Witthooft and co-workers describe a new method for evaluating the bioavailability of folates from foods in humans, using an ileostomy model.

Highlights

  • Folic acid: a key vitamin in nutrition

  • Folic acid, present in different chemical forms of folates in the diet, is essential for cell division, biosynthesis of DNA and RNA, and growth

  • Knowledge of the folate content in different foods, as well as the bioavailability of folates from different foods, is essential. In this issue of the Scandinavian Journal of Nutrition, Cornelia Witthoft and co-workers describe a new method for evaluating the bioavailability of folates from foods in humans, using an ileostomy model

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Summary

Introduction

Folic acid: a key vitamin in nutrition Present in different chemical forms of folates in the diet, is essential for cell division, biosynthesis of DNA and RNA, and growth. Knowledge of the folate content in different foods, as well as the bioavailability of folates from different foods, is essential.

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