Folate, vitamin B12, alpha-tocopherol and selected liver components in periparturient dairy goats supplemented with choline and vitamin E

Abstract

The influence of rumen-protected choline and vitamin E administration on status of folate, vitamin B12, and vitamin E and selected liver components was studied on 4 groups of 12 periparturient dairy goats: control, CTR; choline supplemented, RPC; vitamin E, VITE; choline and vitamin E, RPCE. Plasma folate did not differ between groups, except at parturition when RPC and RPCE goats had higher folate levels than CTR and VITE animals. Neither RPC nor vitamin E affected vitamin B12 plasma concentrations, while a time effect was observed after the third week of lactation, when B12 levels in each group started to increase. Alpha-tocopherol supplementation was associated with increased plasma α-tocopherol in the VITE and RPCE compared to the CRT and RPC groups, while RPC supplementation did not affect a-tocopherol levels in both RPC and RPCE groups compared to CTR and VITE ones. In control and RPC goats liver total lipid did not differ, while DNA contents and their ratio, were respectively higher and lower in RPC supplemented animals. Overall these results suggest that greater choline availability seems to be essential for optimising metabolic health and methyl group status, in dairy ruminants.