Abstract
Archaeosomes are of interest for potential biotechnological applications such as biomaterial delivery. Indeed, the archaeal lipid analogues improve the stability of delivery systems, including oral administration [1,2]. We developed new archaeal lipid analogues equipped with cell targeting ligands such as folic acid (FA) [3]. In vitro transfection efficiencies of formulations including these lipids were evaluated on several cell lines, and have shown good efficiencies at neutral charge ratios and a clear ligand mediated cell internalisation.
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