Abstract
Abstract Focal Segmental Glomerulosclerosis (FSGS) is one of the common causes of nephrotic syndromes, manifested by heavy proteinuria, minimal hematuria and hypoalbuminemia. If left undiagnosed or untreated, FSGS will progressively damage enough glomeruli to cause a fall in Glomerular Filtration Rate (GFR) producing renal failure and require renal replacement therapy. For this reason, early identification and treatment is warranted to delay disease progression. Multiple treatment options such as steroids have been tried but most of these treatments showed partial response, increased relapses after completing treatment course and increased adverse effects due to prolonged use. <span style=mso-bidi-font-size: 10.0pt;font-family: times= new= roman,serif;color:black;mso-themecolor:text1=>Keywords: Adrenocorticotropic hormone; Chronic kidney disease; Focal segmental glomerulosclerosis; Nephrotic syndrome; N ephrotic range proteinuria <span style=font-size:11.0pt; mso-bidi-font-size:10.0pt;line-height:106%;font-family: times= new= roman,serif;= mso-fareast-font-family:calibri;mso-fareast-theme-font:minor-latin;color:black;= mso-themecolor:text1;mso-ansi-language:en-us;mso-fareast-language:en-us;= mso-bidi-language:ar-sa=>Abbreviations: <span style=font-size:10.0pt; line-height:106%;font-family: times= new= roman,serif;mso-fareast-font-family:= calibri;mso-fareast-theme-font:minor-latin;color:black;mso-themecolor:text1;= mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa=> ACTH : Adrenocorticotropic Hormone ; FSGS: <span style=font-size:10.0pt;line-height: 106%;font-family: times= new= roman,serif;mso-fareast-font-family:palatinoltstd-roman;= color:black;mso-themecolor:text1;mso-ansi-language:en-us;mso-fareast-language:= en-us;mso-bidi-language:ar-sa=> <span style=font-size:10.0pt; line-height:106%;font-family: times= new= roman,serif;mso-fareast-font-family:= calibri;mso-fareast-theme-font:minor-latin;color:black;mso-themecolor:text1;= mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa=>Focal Segmental Glomerulosclerosis; <span style=font-size:10.0pt;line-height: 106%;font-family: times= new= roman,serif;mso-fareast-font-family:palatinoltstd-roman;= color:black;mso-themecolor:text1;mso-ansi-language:en-us;mso-fareast-language:= en-us;mso-bidi-language:ar-sa=> GFR: <span style=font-size:10.0pt; line-height:106%;font-family: times= new= roman,serif;mso-fareast-font-family:= calibri;mso-fareast-theme-font:minor-latin;color:black;mso-themecolor:text1;= mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa=> Glomerular Filtration Rate; suPAR: soluble urokinase-type Plasminogen Activator Receptors; CLCF1: Cardiotrophin-like Cytokine Factor-1; MC1R: Melanocortin 1 Receptor; ACEI: Angiotensin Converting Enzyme Inhibitors; MN: Membranous Nephropathy; MCD: Minimal Change Disease
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
