Abstract
Circumscribed and confined infection, commonly expressed as focal infection, has long been recognized as an important etiologic factor in systemic disease. Yet as a principle it has not received sufficient attention from practitioners. In my opinion focal infection is very frequently related to local and general disease. Apparently it is an important factor in some systemic diseases, heretofore unsuspected. For several years, the medical clinic of Rush Medical College and the Presbyterian Hospital has furnished a large number of patients suffering from chronic infectious endocarditis of the malignant type (Streptococcus viridans), arthritis deformans, rheumatic fever, nephritis acute and chronic, myocarditis chronica, exophthalmic goiter, cholecystitis, ulcer (peptic) of stomach, diabetes mellitus, etc. In addition to the usual clinical and laboratory investigations by the members of the clinic, collective and cooperative research has been carried on in connection with the workers of the Otho S. A. Sprague Memorial Institute and the Memorial
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
