Abstract
IntroductionFocal hematopoietic hyperplasia (FHH) is an unusual benign lesion that can rarely involve the ribs. In general, FHHs is a tumor-like expansion of ribs due to the abnormal proliferation of bone marrow. FHHs are mostly found incidentally at radiologic studies performed for other reasons. They are characterized by gradually enlarging osteolytic masses that involve the rib. Presentation of caseHere, we present an unusual case of focal hematopoietic hyperplasia of the rib who arrived to our institute with a complaint of severing back pain at the level of T5-T6 vertebrae. The diagnosis of FHH has been made based on clinical and radiologic findings and confirmed by histopathologic evaluations. We also reviewed all previously reported cases of Focal Hematopoietic hyperplasia of the rib in the literature. DiscussionNone of the previously reported cases, same as our patient, gave a history of trauma to the site involved or family history of malignancy. There was no association with hematological disorders or other malignancies that might have initiated FHH. Histologic evaluations of previously reported cases represented a hyper cellular bone marrow merging with the fatty marrow. The morphology and maturation of all hematopoietic cell lines were normal and there was no report of morphologically abnormal hematopoietic cell or malignant tumor cells. ConclusionPhysicians must consider the FHH among differential diagnosis of secondary rib lesions. Surgical resection is the treatment of choice; the risk of recurrence or metastasis is neglectable.
Highlights
Focal hematopoietic hyperplasia (FHH) is an unusual benign lesion that can rarely involve the ribs
Benign and malignant tumors can be distinguished from each other based on radiologic findings and clinical features [1]
FHHs is a tumor-like expansion of ribs due to the abnormal proliferation of bone marrow
Summary
Focal hematopoietic hyperplasia (FHH) is an unusual benign lesion that can rarely involve the ribs. FHHs is a tumor-like expansion of ribs due to the abnormal proliferation of bone marrow. FHHs are mostly found incidentally at radiologic studies performed for other reasons. They are characterized by gradually enlarging osteolytic masses that involve the rib. We reviewed all previously reported cases of Focal Hematopoietic hyperplasia of the rib in the literature. DISCUSSION: None of the previously reported cases, same as our patient, gave a history of trauma to the site involved or family history of malignancy. Histologic evaluations of previously reported cases represented a hyper cellular bone marrow merging with the fatty marrow. Surgical resection is the treatment of choice; the risk of recurrence or metastasis is neglectable
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.