Abstract
Blood brain barrier(BBB) is one of the major components of central nervous system (CNS) which prevents all kinds of external molecules to infest CNS. However this protection also prevents gene and targeted drug delivery to CNS. The tight junctions of BBB pose as an impermeable wall for components to penetrate within the BBB. Recently an upcoming approach of utilizing Ultrasound with ultrasound contrast components is of intrest to researchers as it allows the penetration of these components without damaging neuronal cell. Using the above technique till now antibodies or plasmid DNA has been successfully delivered into rodents. doi : 10.5214/ans.0972.7531.210107
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