Abstract

The detection of magnetic nanoparticles (MNPs) is essential for applications in biomedicine, specifically in the detection of biological targets such as disease-related proteins and cells, known as magnetic immunoassay [1]. The size of the MNPs varies within a few to tens of nanometers; hence, their sizes are comparable to cells, viruses and proteins. This means that, with proper treatment, MNPs (magnetic markers) can provide a method of ‘marking’ or addressing specific biological entities. With the use of magnetic immunoassay, we can perform immunoassays in the liquid phase; where the bound and unbound markers can be magnetically distinguished by exploiting the difference in the Brownian relaxation time between bound and unbound markers without needing to perform a time-consuming washing process [2].

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