Abstract
Epilepsy represents a personal and major community burden because about one-third of epileptic patients remain resistant to medical treatment. Flupirtine, as a potassium channel opener, can be a rational template for the treatment of epilepsy. To investigate flupirtine +/- celecoxib versus diazepam anticonvulsant role on induced epilepsy in mice. Generalized seizures and status epilepticus were induced by pentylenetetrazole and lithium/pilocarpine, respectively. The latency period to 1st seizure
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Schedule a callMore From: Journal Of Advanced Pharmacy Education And Research
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