Abstract
Radio-fluorogenic (RFG) gels become permanently fluorescent when exposed to high-energy radiation with the intensity of the emission proportional to the local dose of radiation absorbed. An apparatus is described, FluoroTome 1, that is capable of taking a series of tomographic images (thin slices) of the fluorescence of such an irradiated RFG gel on-site and within minutes of radiation exposure. These images can then be compiled to construct a 3D movie of the dose distribution within the gel. The historical development via a laboratory-bench prototype to a readily transportable, user-friendly apparatus is described. Instrumental details and performance tests are presented.
Highlights
Several bulk media have been proposed for the creation of three-dimensional images of the energy deposited in materials by complex fields of high-energy photon or particle radiation [1]
Detailed schematics of the external and internal aspects of the apparatus are shown in Figure 4a,b with downloadable versions given in the supplemental information
4a borosilicate glass cell containing a fluorescent gel or solution is positioned in a holder on the and 4b with downloadable versions given in the supplemental information
Summary
Several bulk media have been proposed for the creation of three-dimensional images of the energy deposited in materials by complex fields of high-energy photon or particle radiation [1] The need for such media has been driven by the increasing sophistication and subtlety of dose delivery in radiotherapy clinics and the requirement for quality control of treatment protocols and equipment [2,3,4]. The use of RFG gels to monitor dose deposition by a variety of radiation sources, from a brachytherapy radioisotope to an 80 MeV proton beam, has been recently reviewed [6] In these early measurements, images of the bulk medium were made.
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