Abstract
Fluoroquinolone-resistant<i>Salmonella</i>Paratyphi A
Highlights
On disk diffusion susceptibility testing, the isolate was resistant to nalidixic acid (NA) and to ofloxacin
Several epidemics of typhoid and paratyphoid fever caused by NA-resistant strains with clinical failure of quinolone treatment have been reported [4,5]
An experimental attempt had been previously made to induce the production of strains with high-level fluoroquinolone resistance by culturing strains of S
Summary
5. Wachsmuth IK, Evins GM, Fields PI, Olsvik O, Popovic T, Bopp CA, et al The molecular epidemiology of cholera in Latin America. Address for correspondence: Ana C.P. Vicente, Departamento de Genética, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Avenida Brasil, 4365, Rio de Janeiro, Brazil, CEP 21045-900; fax: 55-21-22604282; email: anapaulo@ ioc.fiocruz.br Multidrug-resistant strains began to prevail in disease-endemic areas, and former first-line antimicrobial drugs, such as chloramphenicol, were sometimes ineffective [1]. Strains with decreased susceptibility to quinolones have emerged, and clinical treatment failure is a serious concern [2,3,4,5].
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