Abstract

Loss of the three most commonly used fluorocarbon aerosol propellants from various types of containers with different stoppers as a function of time, temperature, and initial concentration was investigated. The loss process was found to continue for at least 3 days. The decreasing order of loss from serum bottles with three types of stoppers was usually: lacquer-coated rubber stopper < regular (plain) rubber stopper < silicone stopper. Significant loss was also with storage in commercially available vacuum tubes. Such mechanisms for loss as adsorption, absorption, complexation, and permeation are discussed.

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