Abstract
Background and Purpose. Several studies have evaluated the role of fluorine-18-fluorodeoxyglucose positron emission tomography and positron emission tomography/computed tomography (FDG-PET and PET/CT) in diagnosing and assessing disease activity in patients with retroperitoneal fibrosis (RF). The aim of our paper is to perform a literature review on this topic. Methods. Scientific articles that evaluated the usefulness of FDG-PET and PET/CT in patients with RF were searched and discussed. Results. Eleven studies were found, and the main findings of these articles were described. Conclusion. FDG-PET and PET/CT are useful functional imaging methods for assessing patients with RF both in the diagnosis and in the treatment response evaluation. Moreover, further studies are needed to substantiate the role of FDG-PET and PET/CT in patients with RF.
Highlights
Retroperitoneal fibrosis (RF) is a chronic inflammatory disease, characterized by the presence of retroperitoneal inflammatory tissue, typically surrounding abdominal aorta and/or iliac arteries, and often leading to the involvement of adjacent structures, more frequently the ureters and inferior vena cava [1,2,3,4,5,6,7].retroperitoneal fibrosis (RF) is a complex clinical entity still incompletely defined and with unclear etiology
RF in the presence of aortic atheromatous inflammation has been included, more than twenty years ago, among the secondary forms, since this condition appears to be elicited by antigen-acting oxidizedLDL and/or ceroid, that are present within the atheromatous plaque
Etiology of other secondary RF refers to medications, infections, traumas, surgery, radiation therapy, and malignancies [1,2,3,4,5,6,7]
Summary
Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography in Assessing Retroperitoneal Fibrosis: A Literature Review. Several studies have evaluated the role of fluorine-18-fluorodeoxyglucose positron emission tomography and positron emission tomography/computed tomography (FDG-PET and PET/CT) in diagnosing and assessing disease activity in patients with retroperitoneal fibrosis (RF). The aim of our paper is to perform a literature review on this topic. Scientific articles that evaluated the usefulness of FDG-PET and PET/CT in patients with RF were searched and discussed. The main findings of these articles were described. FDG-PET and PET/CT are useful functional imaging methods for assessing patients with RF both in the diagnosis and in the treatment response evaluation. Further studies are needed to substantiate the role of FDG-PET and PET/CT in patients with RF
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