Abstract
This single-blind, randomized, crossover study aimed at assessing the long-term fluoride concentrations in saliva and in dental biofilm after different home-use fluoride treatments. The study volunteers (n = 38) were residents of an area with fluoridated drinking water. They were administered four treatments, each of which lasted for one week: twice-daily placebo dentifrice, twice-daily fluoride dentifrice, twice-daily fluoride dentifrice and once-daily fluoride mouthrinse, and thrice-daily fluoride dentifrice. At the end of each treatment period, samples of unstimulated saliva and dental biofilm were collected 8 h after the last oral hygiene procedure. Fluoride concentrations in saliva and dental biofilm were analyzed using a specific electrode. The fluoride concentrations in saliva and dental biofilm 8 h after the last use of fluoride products did not differ among treatments. The results of this study suggest that treatments with home-use fluoride products have no long-term effect on fluoride concentrations in saliva and in dental biofilm of residents of an area with a fluoridated water supply.
Highlights
Fluoride is thought to exert anti-caries effects predominantly by elevating the fluoride concentrations in saliva and dental biofilm.[1]
Since the literature remains inconclusive in regard to this aspect, the aim of this study was to determine the fluoride retention in saliva and in dental biofilm after different home-use fluoride treatments in volunteers living in an area with a fluoridated water supply
Two volunteers were excluded because they failed to attend one or more appointments and their saliva and dental biofilm samples were not included in the data analysis
Summary
Fluoride is thought to exert anti-caries effects predominantly by elevating the fluoride concentrations in saliva and dental biofilm.[1]. Because a mouthrinse is usually applied immediately after the toothbrush procedure, it does not increase the frequency of fluoride exposure.[6]
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