Abstract
The distribution of fluoride-resistant acid phosphatase, substance P and somatostatin were investigated in the dorsal horn of the spinal cord and in dorsal root ganglia. In the dorsal horn, the distribution of fluoride-resistant acid phosphatase closely paralleled that of somatostatin and only partly overlapped with that of substance P. In sensory ganglia, none of the fluoride-resistant acid phosphatasecontaining neurones contained either substance P or somatostatin. The results suggest the existence of a population of fluoride-resistant acid phosphatase-positive sensory neurones which is distinct from neurones containing either of these peptides.
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