Abstract
Fluoride induced alterations in arginase activity in liver, muscle, kidney, gill and brain of freshwater cat fish, Clarias batrachus (Linn.) were carried out. The effect of fluoride was observed in different concentrations like 1, 10, 20 and 30 ppm in 1, 30 and 60 days of exposure. The arginase activity was found increased in all the tissues, throughout the exposure span. Maximum activity was observed on 60th day of exposure in 30 ppm of fluoride concentration. In most of the cases the elevation of arginase activity significantly differed from the controls. Gill showed maximum activity followed by liver, brain, kidney, and muscle. The increase in arginase activity indicates production of urea or ornithine.
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