Fluorescence switching of BSA–[Fe(III)–salen]Cl and implementation of its multiple logic gates

Abstract

In this study, [Fe(III)–salen]Cl (complex 1) was synthesized and its interaction with bovine serum albumin (BSA) was investigated by fluorescence spectroscopy. The estimated distance between BSA and 1 indicated that energy transfer from the excited state of BSA to 1 was achieved with high efficiency. BSA sensors based on fluorescent off–on (1- Na2H2EDTA) and on–off (OH−–H+) were examined and the results confirmed that BSA could operate as molecular logic gate upon interaction with 1, Na2H2EDTA, and OH− as chemical inputs. Multiple logic gates including NOR, NOT, and IMP were constructed through consecutive association of 1 with BSA.