Abstract
Recurrence within the neoterminal ileum is a frequent and unexplained event occurring early after ileocolonic resection for Crohn's disease. 1 Rutgeerts P Geboes K Vantrappen G Beyls J Kerremans R Hiele M. Predictability of the postoperative course of Crohn's disease. Gastroenterology. 1990; 99: 956-963 Abstract PubMed Google Scholar Osborne et al. 2 Osborne MJ Hudson M Piasecki C et al. Crohn's disease and anastomotic recurrence: microvascular ischaemia and anastomotic healing in an animal model. Br J Surg. 1993; 80: 226-229 Crossref PubMed Scopus (36) Google Scholar have shown that ischemic insults resulting from microvascular injury can produce a pattern of intestinal inflammation similar to that seen in anastomotic recurrence in Crohn's disease. Intestinal ischemia secondary to vasculitis might then be responsible for the features of the disease. However, such a hypothesis has never been demonstrated in vivo. The present study aimed to evaluate the pre-anastomotic mucosal microcirculation in patients endoscopically observed after surgical resection with a new endoscopic method of fluorescence imaging reported recently by Franzeck et al. 3 Franzeck UK Münch R Wächter M Vesti B Ammann R Bollinger A Dynamic fluorescence video endoscopy for intravital evaluation of gastrointestinal mucosal blood flow. Gastrointest Endosc. 1993; 39: 806-809 Abstract PubMed Scopus (8) Google Scholar
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