Fluorescein angiographic features of tubulointerstitial nephritis and uveitis syndrome

Abstract

Objective To explain fluorescein angiographic features in patients with tubulointerstitial nephritis and uveitis syndrome. Design Retrospective observational case series. Participants Four consecutive patients with tubulointerstitial nephritis and uveitis syndrome seen at Uveitis Service of Okayama University Hospital from 1995 to 2000. Methods Patients’ characteristics obtained from medical records were analyzed. In addition, characteristics of 15 patients reported previously as case reports in the Japanese literature were reviewed. Main outcome measures Clinical and fluorescein angiographic features. Results The present four patients showed varying degrees of retinal capillary leakage on fluorescein angiography, ranging from capillary leakage limited to the peripheral fundus to cystoid macular edema. The same angiographic features were found in 15 patients reported previously in the Japanese literature. Conclusions Retinal capillary leakage of varying degrees was a common fluorescein angiographic feature in patients with tubulointerstitial nephritis and uveitis syndrome. Fluorescein angiography is valuable in assessing the extent of retinal involvement.